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VOL. 8, ISSUE 1 (2026)
Chemical composition of ibuprofen determined by IR spectroscopy
Authors
Ioana Stanciu
Abstract
In this article, we
determined the composition of ibuprofen by IR spectroscopy using the
PerkinElmer FT-IR System spectrometer. Ibuprofen has absorption bands between
3300 and 550cm-1. Ibuprofen is a nonsteroidal anti-inflammatory drug
(NSAID) derived from propionic acid, structurally characterized by the presence
of a substituted aromatic nucleus and a carboxylic group that confers its
pharmacological properties. The active substance,
(RS)-2-(4-isobutylphenyl)propionic acid, is a racemic mixture, of which the S
enantiomer exhibits the main anti-inflammatory activity. Commercial
pharmaceutical formulations include, in addition to the active ingredient,
excipients specific to the presentation form — such as binding, filling,
disaggregation, sweetening or stabilizing agents — designed to ensure the
stability, absorption and tolerability of the drug. The chemical composition
and excipients used contribute to the anti-inflammatory, analgesic and
antipyretic profile of ibuprofen, making it one of the most widely used NSAIDs
in medical practice.
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Pages:1-2
How to cite this article:
Ioana Stanciu "Chemical composition of ibuprofen determined by IR spectroscopy". International Journal of Educational Research and Studies, Vol 8, Issue 1, 2026, Pages 1-2
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