ARCHIVES
VOL. 5, ISSUE 1 (2023)
The effects of Robusta coffee on blood fibrinogen level rat induced high fat diet
Authors
Nadie Fatimatuzzahro, Rendra Christedy Prasetya
Abstract
Hyperlipidemia is one of the risk factors of stroke and
atherosclerosis. Hyperlipidemia is a condition of increasing fat levels in the
blood, especially for Low density Lipoprotein (LDL). Increased LDL can cause
the increasing of oxidation level in the blood, from LDL to become oxidative
LDL which is one of the risk factors for chronic inflammation. Fibrinogen
levels is one of major inflammatory marker. Fibrinogen levels in blood plasma increase
if there was inflammation, and causes high blood viscosity. It is a risk factor
for ischemic stroke, hemorrhagic stroke or atherosclerosis. Prevention efforts
and treatment to reduce hyperlipidemia can be done by using herbal plants, one
of which is robusta coffee. Robusta coffee has anti-inflammatory and
antioxidant properties that are thought to be effective in reducing
inflammation as indicated by reduced levels of fibrinogen. This study aimed to
analyze the potential of Robusta coffee as natural anti-inflammatory and
antioxidant, by analyzing the level of fibrinogen in rat induced high fat diet.
Fiveteen male wistar rats were randomly divided into 3 groups including control
(K), high-fat diet (H), and high-fat diet + robusta coffee (C). High-fat diet
induced by feeding the yolks of duck and pork oil. The measurement of
fibrinogen levels is done by calculating the differences in plasma protein
levels in incubated blood (Heat Precipitating Method). Robusta coffee was reduced
the fibrinogen levels in rat induced high-fat diet.
Download
Pages:55-57
How to cite this article:
Nadie Fatimatuzzahro, Rendra Christedy Prasetya "The effects of Robusta coffee on blood fibrinogen level rat induced high fat diet". International Journal of Educational Research and Studies, Vol 5, Issue 1, 2023, Pages 55-57
Download Author Certificate
Please enter the email address corresponding to this article submission to download your certificate.