Government of India approved National Education Policy 2020 (NEP). This is the first policy of 21^st century on education systems. It has envisioned autonomous higher education colleges and multi-disciplinary universities. The UGC and AICTE have been granting autonomy to existing colleges based on quality education provided by them. Now the NEP 2020 envision all colleges and universities as autonomous institutions. It is a big challenge for universities and colleges to become autonomous which will be based on quality of education, research, services and accreditation. Another challenge is sustaining autonomy of the institution and move to higher ladder of accreditation and autonomy. In this paper strategies for obtaining and sustaining autonomy are stated at central government, state government, institute, faculty members and students level.